Airway Hyperresponsiveness: An Unsung Clinical Manifestation
نویسندگان
چکیده
منابع مشابه
The relationship of airway hyperresponsiveness and airway inflammation: Airway hyperresponsiveness in asthma: its measurement and clinical significance.
Airway hyperresponsiveness (AHR) is a clinical feature of asthma and is often in proportion to the underlying severity of the disease. To understand AHR and the mechanisms that contribute to these processes, it is helpful to divide the airway components that affect this feature of asthma into "persistent" and "variable" categories. The persistent component of AHR represents structural changes i...
متن کاملVirus-induced Airway Hyperresponsiveness
Intratracheal inoculation of parainfluenza type 3 virus to guinea pigs induces a marked increase in airway responsiveness in vivo and in vitro. In spontaneously breathing anesthetized guinea pigs inhalation of an aerosol containing the nitric oxide (NO) precursor L-argimine (2.0 mM) completely prevented the virus-induced airway hyperresponsiveness to histamine. In addition, perfusion of L-argin...
متن کاملConclusion: Airway hyperresponsiveness in asthma: its measurement and clinical significance.
or indirect challenges with inhaled mannitol 2 or exercise 3 is important in establishing a correct diagnosis. This is particularly true in excluding asthma as a diagnosis in patients with symptoms that suggest asthma, but are caused by another condition. This is because airway hyperresponsiveness measurements are very sensitive in determining a diagnosis of asthma (therefore, they have a high ...
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Pellagra, a disease rarely seen in developed countries today, was common during the first half of this century in the United States. The disease was initially believed to be infectious, and severe "pellagraphobia" left many victims and their families ostracized. This paper calls attention to Joseph Goldberger, an American physician whose remarkable research helped correct the erroneous belief i...
متن کاملAirway Hyperresponsiveness in Asthma: Mechanisms, Clinical Significance, and Treatment
Airway hyperresponsiveness (AHR) and airway inflammation are key pathophysiological features of asthma. Bronchial provocation tests (BPTs) are objective tests for AHR that are clinically useful to aid in the diagnosis of asthma in both adults and children. BPTs can be either "direct" or "indirect," referring to the mechanism by which a stimulus mediates bronchoconstriction. Direct BPTs refer to...
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ژورنال
عنوان ژورنال: Journal of Allergy & Therapy
سال: 2016
ISSN: 2155-6121
DOI: 10.4172/2155-6121.1000235